| Date | Team | Money | Spread | Totals |
|---|---|---|---|---|
| Sunday, Sep 25, 01:00 pm |
Baltimore Ravens at | -140 | -2.5 (-110) | O: 44.0 (-110) |
| New England Patriots | +120 | 2.5 (-110) | U: 44.0 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Buffalo Bills at | -230 | -5.0 (-110) | O: 53.0 (-110) |
| Miami Dolphins | +185 | 5.0 (-110) | U: 53.0 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Cincinnati Bengals at | -255 | -6.5 (-110) | O: 45.0 (-110) |
| New York Jets | +205 | 6.5 (-110) | U: 45.0 (-110) | |
| Sunday, Sep 25, 01:00 pm |
New Orleans Saints at | -140 | -2.5 (-110) | O: 41.0 (-110) |
| Carolina Panthers | +120 | 2.5 (-110) | U: 41.0 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Detroit Lions at | +210 | 6.0 (-110) | O: 52.5 (-110) |
| Minnesota Vikings | -260 | -6.0 (-110) | U: 52.5 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Kansas City Chiefs at | -250 | -5.5 (-110) | O: 51.0 (-110) |
| Indianapolis Colts | +200 | 5.5 (-110) | U: 51.0 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Las Vegas Raiders at | -130 | -2.0 (-110) | O: 45.5 (-110) |
| Tennessee Titans | +110 | 2.0 (-110) | U: 45.5 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Philadelphia Eagles at | -295 | -6.5 (-110) | O: 47.5 (-110) |
| Washington Commanders | +235 | 6.5 (-110) | U: 47.5 (-110) | |
| Sunday, Sep 25, 01:00 pm |
Houston Texans at | +130 | 2.5 (even) | O: 39.0 (-110) |
| Chicago Bears | -155 | -2.5 (-120) | U: 39.0 (-110) | |
| Sunday, Sep 25, 04:05 pm |
Jacksonville Jaguars at | +145 | 3.0 (even) | O: 42.5 (-110) |
| Los Angeles Chargers | -175 | -3.0 (-120) | U: 42.5 (-110) | |
| Sunday, Sep 25, 04:25 pm |
Green Bay Packers at | even | 1.0 (-110) | O: 42.0 (-110) |
| Tampa Bay Buccaneers | -120 | -1.0 (-110) | U: 42.0 (-110) | |
| Sunday, Sep 25, 04:25 pm |
Atlanta Falcons at | even | 1.0 (-110) | O: 42.0 (-110) |
| Seattle Seahawks | -120 | -1.0 (-110) | U: 42.0 (-110) | |
| Sunday, Sep 25, 04:25 pm |
Los Angeles Rams at | -195 | -3.5 (-105) | O: 48.5 (-110) |
| Arizona Cardinals | +160 | 3.5 (-115) | U: 48.5 (-110) | |
| Sunday, Sep 25, 08:20 pm |
San Francisco 49ers at | -130 | -1.5 (-110) | O: 44.0 (-110) |
| Denver Broncos | +110 | 1.5 (-110) | U: 44.0 (-110) | |
| Monday, Sep 26, 08:15 pm |
Dallas Cowboys at | -105 | 1.0 (-110) | O: 39.0 (-110) |
| New York Giants | -115 | -1.0 (-110) | U: 39.0 (-110) |